Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (20,884)	$ (58,013)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock based compensation – consultants and research and development	2,522	16,695
Stock based compensation - officers, employees and board of directors	2,092	16,983
Stock based compensation - vested stock options	3,032	251
Fair value of common stock issued to a noteholder as settlement	35
Convertible notes payable issued for consulting services		720
Change in fair value of derivative liability	(119)	(211)
Change in operating lease right-of-use assets	95
Gain from extinguishment of line of credit	(31)
Unrealized loss on marketable securities	30	29
Changes in operating assets and liabilities:
Decrease in prepaid expenses and other current assets	136	174
(Increase) in deposits	(9)
(Decrease) increase in accounts payable and accrued expenses	(2,030)	7,077
Decrease in operating lease liability	(86)
Increase in accrued interest		689
Net Cash Used in Operating Activities	(15,217)	(15,606)
CASH FLOWS FROM INVESTING ACTIVITIES
Sales (purchases) of investments	12,145	(23,040)
Net Cash Provided by (Used in) Investing Activities	12,145	(23,040)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from issuance of common stock		24,679
Cancellation of common stock upon settlement with former officer	(224)
Proceeds from exercise of warrants		16,433
Proceeds from issuance of notes payable		1,205
Net Cash (Used in) Provided by Financing Activities	(224)	42,317
Net (Decrease) Increase in Cash	(3,296)	3,671
Cash at Beginning of Period	8,968	5,297
Cash at End of Period	5,672	8,968
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
Interest
Income taxes
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING ACTIVITIES
Right-of-use assets exchanged for lease liabilities	260
Extinguishment of unamortized debt discount and adjustment to accumulated deficit upon adoption of ASU 2020-06		4,745
Common stock issued upon conversion of notes payable and accrued interest		38,799
Common stock issued upon settlement of vendor payable	3,251
Accounts payable reclassified to convertible notes		525
Extinguishment of derivative liabilities		35
Conversion of Series J Preferred Stock to Common Stock		$ 2