Quarterly report pursuant to Section 13 or 15(d)

Note 1 - The Company and Summary of Significant Accounting Policies (Details Narrative)

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Note 1 - The Company and Summary of Significant Accounting Policies (Details Narrative) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Accounting Policies [Abstract]            
Accumulated deficit $ (565,862)   $ (565,862)   $ (528,685)  
Cash and cash equivalent 313 $ 1,232 $ 313 $ 1,232 $ 60 $ 576
Diluted shares excluded from calcuation of EPS     73,520,680 2,977,958    
Research and development $ 671 $ 1,111 $ 1,659 $ 7,835