Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies (Details Narrative)

v3.24.2.u1
Commitments and Contingencies (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 20, 2024
May 13, 2024
May 13, 2022
Jun. 16, 2021
Mar. 26, 2021
Jul. 18, 2016
May 31, 2024
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Apr. 25, 2024
Dec. 31, 2023
Aug. 24, 2022
Loss Contingencies [Line Items]                            
Loss Contingency, Damages Sought, Value     $ 470,000                      
Treasury Stock, Common, Shares     13,902                      
Legal fee             $ 473,000              
Shares return, value             $ 19,000              
Shares return             13,902              
Common stock, shares issued               2,234,328   2,234,328     1,380,633  
Accounts payable, current               $ 1,717,000   $ 1,717,000     $ 4,328,000  
Beneficial ownership percentage               5.00%   5.00%        
Stock issued during period, value, issued for services                 $ 1,500,000 $ 315,000      
Research and development expense               $ 1,784,000 $ 2,095,000 2,561,000 3,745,000      
Scientific Research Agreement [Member]                            
Loss Contingencies [Line Items]                            
Aggregate research and development expense       $ 2,100,000                    
Research and development expense                   0 192,000      
Unbilled and unaccrued amounts               0   0        
Sponsored Research Agreement [Member]                            
Loss Contingencies [Line Items]                            
Aggregate research and development expense $ 1,700,000                          
Research and development expense                   863,000 0      
Unbilled and unaccrued amounts               $ 862,000   862,000        
2016 Patent Exclusive License Agreement [Member]                            
Loss Contingencies [Line Items]                            
Research and development expense                   0 0      
Proceeds from upfront amount   $ 145,000       $ 200,000                
Maintenance fee   100,000       100,000                
Performance milestone payments   3,100,000       3,100,000                
Sales milestone payments   1,000,000       1,000,000                
Gross sales   250,000,000       250,000,000                
Sales revenue   5,000,000       5,000,000                
Cumulative gross sales   500,000,000       $ 500,000,000                
[custom:RoyaltyExpenseYearOne]   250,000                        
[custom:RoyaltyExpenseYearTwoThroughFive]   2,000,000                        
[custom:RoyaltyExpenseYearAfterSix]   $ 5,000,000                        
2016 Patent Exclusive License Agreement [Member] | Minimum [Member]                            
Loss Contingencies [Line Items]                            
Net sales percentage   1.00%       4.00%                
2016 Patent Exclusive License Agreement [Member] | Maximum [Member]                            
Loss Contingencies [Line Items]                            
Net sales percentage   5.00%       6.00%                
2016 Patent Exclusive License Agreement [Member] | 2017 through 2012 [Member]                            
Loss Contingencies [Line Items]                            
Maintenance fee           $ 200,000                
2016 Patent Exclusive License Agreement [Member] | 2022 [Member]                            
Loss Contingencies [Line Items]                            
Annual royalty payments           250,000                
2016 Patent Exclusive License Agreement [Member] | 2025 [Member]                            
Loss Contingencies [Line Items]                            
Maintenance fee   $ 50,000                        
Annual royalty payments           2,000,000                
2016 Patent Exclusive License Agreement [Member] | 2027 [Member]                            
Loss Contingencies [Line Items]                            
Annual royalty payments           $ 5,000,000                
2021 Patent License Agreement [Member]                            
Loss Contingencies [Line Items]                            
Research and development expense                   $ 145,000 $ 0      
Maintenance fee         $ 2,000,000                  
Annual royalty payments         250,000                  
Performance milestone payments         3,100,000                  
Sales milestone payments         1,000,000                  
Gross sales         250,000,000                  
Sales revenue         5,000,000                  
Cumulative gross sales         500,000,000                  
Upfront license fee         20,000                  
License maintenance fee, receivable         $ 5,000                  
2021 Patent License Agreement [Member] | Minimum [Member]                            
Loss Contingencies [Line Items]                            
Net sales percentage         2.50%                  
2021 Patent License Agreement [Member] | Maximum [Member]                            
Loss Contingencies [Line Items]                            
Net sales percentage         5.00%                  
Cytovance Biologics Inc [Member]                            
Loss Contingencies [Line Items]                            
Common stock, shares issued               127,597 44,793 127,597 44,793      
Accounts payable, current               $ 810,000 $ 1,120,000 $ 810,000 $ 1,120,000      
Cytovance Biologics Inc [Member]                            
Loss Contingencies [Line Items]                            
Equity method investment, ownership percentage                       9.90%   4.90%