Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (58,013)	$ (28,296)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock based compensation - consultants and research and development	16,695
Stock based compensation - officers, directors and employees	17,234	269
Convertible notes payable issued for consulting services	720
Amortization of debt discount		317
Convertible notes payable issued and fair value of amended convertible notes payable and warrants as part of forbearance agreements		12,598
Convertible notes payable issued and fair value of common shares and warrants issued as part of legal settlements		5,003
Loss on abandonment of lease		60
Change in fair value of derivative liability	(211)	230
Unrealized loss on marketable securities	29
Issuance of warrants accounted as derivative liability		153
Changes in operating assets and liabilities:
(Increase) decrease in prepaid expenses	174	242
Increase (decrease) in accounts payable and accrued expenses	7,077	(838)
Increase in accrued interest	689	3,000
Net Cash Used in Operating Activities	(15,606)	(7,262)
CASH FLOWS FROM INVESTING ACTIVITIES
Purchases of investments	(23,040)
Net Cash Used in Investing Activities	(23,040)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from exercise of warrants	16,433
Proceeds from issuance of common stock	24,679
Proceeds from issuance of convertible notes payable	1,205	12,531
Net Cash Provided by Financing Activities	42,317	12,531
Net Increase in Cash	3,671	5,269
Cash at Beginning of Period	5,297	28
Cash at End of Period	8,968	5,297
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:
Interest
Income taxes paid
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING ACTIVITIES
Extinguishment of unamortized debt discount and adjustment to accumulated deficit upon adoption of ASU 2020-06	4,745
Beneficial conversion feature of notes payable issued for cash		4,745
Common stock issued upon conversion of notes payable and accrued interest	38,799	1,741
Accounts payable reclassified to convertible notes	525
Extinguishment of derivative liability	35
Conversion of Series J Preferred Stock to Common Stock	2
Convertible notes payable issued for consulting services		360
Reclassification of lease liability to accrued expenses		$ 58