Quarterly report pursuant to Section 13 or 15(d)

Note 1 - The Company and Summary of Significant Accounting Policies (Details Narrative)

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Note 1 - The Company and Summary of Significant Accounting Policies (Details Narrative) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Accounting Policies [Abstract]            
Accumulated deficit $ (535,984)   $ (535,984)   $ (528,685)  
Cash and cash equivalent 264 $ 1,096 $ 264 $ 1,096 $ 60 $ 576
Diluted shares excluded from calcuation of EPS     39,416,352 3,390,120    
Research and development $ 154 $ 3,251 $ 988 $ 6,724