Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies (Details Narrative)

v3.24.3
Commitments and Contingencies (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended
May 20, 2024
May 13, 2024
Jun. 16, 2021
Mar. 26, 2021
Jul. 18, 2016
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Jun. 30, 2024
Apr. 25, 2024
Dec. 31, 2023
Aug. 24, 2022
Loss Contingencies [Line Items]                          
Common stock, shares issued           2,234,328   2,234,328       1,380,633  
Accounts payable, current           $ 2,612,000   $ 2,612,000       $ 4,328,000  
Stock issued during period, value, issued for services             $ 115,000 1,300,000 $ 430,000        
Research and development expense           1,307,000 $ 1,364,000 3,868,000 5,109,000        
2021 Scientific Research Agreement [Member]                          
Loss Contingencies [Line Items]                          
Aggregate research and development expense     $ 2,100,000                    
Research and development expense               0 192,000        
Unbilled and unaccrued amounts           0   0          
2023 Sponsored Research Agreement [Member]                          
Loss Contingencies [Line Items]                          
Aggregate research and development expense $ 1,700,000                        
Research and development expense               863,000 0        
Unbilled and unaccrued amounts           $ 862,000   862,000          
2016 Patent Exclusive License Agreement [Member]                          
Loss Contingencies [Line Items]                          
Research and development expense               145,000 0        
Proceeds from upfront amount   $ 145,000     $ 200,000                
Maintenance fee   100,000     $ 100,000                
Royalty fee percentage         4.00%                
Performance milestone payments   3,100,000     $ 3,100,000                
Sales milestone payments   1,000,000     1,000,000                
Gross sales   250,000,000     250,000,000                
Sales revenue   5,000,000     5,000,000                
Cumulative gross sales   500,000,000     $ 500,000,000                
Royalty expense   250,000                      
Royalty expense   2,000,000                      
Royalty expense   $ 5,000,000                      
2016 Patent Exclusive License Agreement [Member] | Maximum [Member]                          
Loss Contingencies [Line Items]                          
Royalty fee percentage   5.00%     6.00%                
2016 Patent Exclusive License Agreement [Member] | Minimum [Member]                          
Loss Contingencies [Line Items]                          
Royalty fee percentage   1.00%                      
2016 Patent Exclusive License Agreement [Member] | 2017 through 2020 [Member]                          
Loss Contingencies [Line Items]                          
Maintenance fee         $ 200,000                
2016 Patent Exclusive License Agreement [Member] | 2022 [Member]                          
Loss Contingencies [Line Items]                          
Annual royalty payments         250,000                
2016 Patent Exclusive License Agreement [Member] | 2025 [Member]                          
Loss Contingencies [Line Items]                          
Maintenance fee   $ 50,000                      
Annual royalty payments         2,000,000                
2016 Patent Exclusive License Agreement [Member] | 2027 [Member]                          
Loss Contingencies [Line Items]                          
Annual royalty payments         $ 5,000,000                
2021 Patent License Agreement [Member]                          
Loss Contingencies [Line Items]                          
Maintenance fee       $ 2,000,000                  
Annual royalty payments       250,000                  
Performance milestone payments       3,100,000                  
Sales milestone payments       1,000,000                  
Gross sales       250,000,000                  
Sales revenue       5,000,000                  
Cumulative gross sales       500,000,000                  
Upfront license fee       20,000                  
License maintenance fee, receivable       $ 5,000                  
2021 Patent License Agreement [Member] | Maximum [Member]                          
Loss Contingencies [Line Items]                          
Royalty fee percentage       5.00%                  
2021 Patent License Agreement [Member] | Minimum [Member]                          
Loss Contingencies [Line Items]                          
Royalty fee percentage       2.50%                  
Cytovance Biologics Inc [Member]                          
Loss Contingencies [Line Items]                          
Research and development expenses               1,365,000 3,691,000        
Cash payments               $ 3,432,000 $ 1,710,000        
Common stock, shares issued           127,597 57,437 127,597 57,437        
Accounts payable, current           $ 810,000 $ 1,120,000 $ 810,000 $ 1,120,000        
Cytovance Biologics Inc [Member] | Research and Development Expense [Member]                          
Loss Contingencies [Line Items]                          
Research and development expenses               $ 1,365,000 $ 3,691,000        
Cytovance Biologics Inc [Member]                          
Loss Contingencies [Line Items]                          
Equity method investment, ownership percentage                   5.00% 9.90%   4.90%