Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited)

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Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($)
$ in Thousands
Preferred Stock [Member]
Common Stock [Member]
Common Shares Issuable [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Total
Beginning balance, value at Dec. 31, 2020 $ 3 $ 5 $ 566,356 $ (595,797) $ (29,433)
Beginning balance, shares at Dec. 31, 2020 2,450,000 5,218,000      
Equity compensation to officers and board of directors $ 4 14,292 14,296
Equity compensation to officers and board of directors, shares   3,641,000        
Issuance of common stock for services $ 2 8,450 8,452
Issuance of common stock for services, shares   1,957,000        
Extinguishment of debt discount upon adoption of ASU 2020-06 (4,745) 226 (4,519)
Conversion of Preferred Series J-1 to common stock $ (2) $ 1 1
Conversion of Preferred Series J-1 to common stock, Shares (2,354,000) 692,000        
Common shares issued upon mandatory conversion of notes payable and accrued interest $ 4 $ 25,956 12,846 38,806
Common shares issued upon mandatory conversion of notes payable and accrued interest, Shares   3,779,000 7,634,000      
Common shares issued upon exercise of warrants 58 58
Common shares issued upon exercise of warrants, Shares   95,000        
Issuance of common stock in public offering, net of cost $ 5 24,674 24,679
Issuance of common stock in public offering, net of cost, Shares   4,945,000        
Issuance of common stock for research and development agreement 1,355 1,355
Issuance of common stock for research and development agreement, Shares   190,000        
Net loss (29,677) (29,677)
Ending balance, value at Mar. 31, 2021 $ 1 $ 21 $ 25,956 623,287 (625,248) 24,017
Ending balance, shares at Mar. 31, 2021 96,000 20,517,000 7,634,000      
Beginning balance, value at Dec. 31, 2021 $ 1 $ 32 $ 1,113 674,348 (653,584) 21,910
Beginning balance, shares at Dec. 31, 2021 96,000 32,062 327,000      
Cancellation of common stock
Cancellation of common stock, shares   (291)        
Issuance of common shares for common shares issuable $ (1,113) 1,113
Issuance of common shares as equity, shares   327        
Stock Issued During Period, Shares, Conversion of Convertible Securities     (327,000)      
Equity compensation to officers and board of directors 447 447
Equity compensation to officers and board of directors, shares   85,000        
Issuance of common stock for services 872 872
Issuance of common stock for services, shares   163,000        
Net loss   (5,440) (5,440)
Ending balance, value at Mar. 31, 2022 $ 1 $ 32 $ 676,780 $ (659,024) $ 17,789
Ending balance, shares at Mar. 31, 2022 96,000 32,346,000