FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  BRISTOL INVESTMENT FUND LTD
 2. Date of Event Requiring Statement (Month/Day/Year)
01/13/2016		 3. Issuer Name and Ticker or Trading Symbol
OXIS INTERNATIONAL INC [OXIS]
(Last)
(First)
(Middle)
C/O BRISTOL CAPITAL ADVISORS, LLC, 1100 GLENDON AVE., SUITE 1100		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

LOS ANGELES, CA 90024		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 2,441,148
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Convertible notes (1)   (2) 02/15/2016(3) Common Stock 3,912,447 $ 1.25 (4) D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
BRISTOL INVESTMENT FUND LTD
C/O BRISTOL CAPITAL ADVISORS, LLC
1100 GLENDON AVE., SUITE 1100
LOS ANGELES, CA 90024		     X    
BRISTOL CAPITAL LLC
1100 GLENDON AVE., SUITE 850
LOS ANGELES, CA 90024		     X    

Signatures

Bristol Investment Fund Ltd., By: /s/ Paul Kessler, its Director 01/25/2016
**Signature of Reporting Person Date
Bristol Capital LLC, By: /s/ Paul Kessler, its Manager 01/25/2016
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Subject to conversion pursuant to Note Conversion Agreement.
(2) At option of holder.
(3) Subject to extension under certain conditions.
(4) Or 75% of purchase price of next financing if such price under $1.675.
 
Remarks:
Holdings reported herein are the collective holdings of Bristol Investment Fund, Ltd. ("BIF") and Bristol Capital, LLC ("BC"). Paul Kessler, a Director of BIF and Manager of BC, has voting and investment control over the securities held by BIF and BC. As of the date of this filing, BIF holds 2,080,347 shares of the Issuer's common stock, and convertible notes subject to conversion under certain conditions pursuant to a Note Conversion Agreement into a maximum of 3,411,947 shares of the Issuer's common stock; BC holds 360,801 shares of the Issuer's common stock, and convertible notes subject to conversion under certain conditions pursuant to a Note Conversion Agreement into a maximum of 500,500 shares of the Issuer's common stock.

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