Exhibit 21.1

SUBSIDIARIES OF OXIS INTERNATIONAL, INC.


As of December 31, 2005, the Company’s subsidiaries were as follows:

Name
  
Jurisdiction of incorporation
     
OXIS Health Products, Inc.
  
Delaware
OXIS Therapeutics, Inc.
  
Delaware
OXIS International S.A.
  
France
OXIS Acquisition Corporation
  
Delaware
OXIS Isle of Man Limited
  
Isle of Man
OXIS Instruments, Inc.
  
Pennsylvania
BioCheck, Inc.
  
California