GT
BIOPHARMA, INC.
9350
Wilshire Blvd.
Suite
203
Beverly
Hills, CA 90212
April
23, 2021
Via
EDGAR Submission
United
States Securities and Exchange Commission
Division of
Corporation Finance
Office
of Life Sciences
100 F
Street, N.E.
Washington, D.C.
20549
Attention: Chris Edwards
Registration
Statement on Form S-1
CIK No.
0000109657
SEC
Registration No. 333-255429
Ladies
and Gentlemen:
In
accordance with Rule 461 of Regulation C of the General Rules and
Regulations under the Securities Act of 1933, as amended, we hereby
request acceleration of the effective date of the Registration
Statement on Form S-1 (File No. 333-255429) (the
“Registration
Statement”) of GT Biopharma, Inc. (the
“Company”). We
respectfully request that the Registration Statement become
effective as of 5:00 p.m., Eastern Time, on April 27, 2021, or as
soon as practicable thereafter. Once the Registration Statement has
been declared effective, please orally confirm that event with our
counsel, Baker & McKenzie LLP by calling Roger Bivans at (214)
978-3095.
Thank
you for your assistance with this matter.
Michael
Handelman
Chief
Financial Officer
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