Exhibit 107

Calculation of Filing Fee Tables

Form S-1

(Form Type)

GT Biopharma, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

		Security Type		Security Class Title				Fee Calculation or Carry Forward Rule				Amount Registered				Proposed Maximum Offering Price Per Unit				Maximum Aggregate Offering Price				Fee Rate				Amount of Registration Fee				Carry Forward Form Type				Carry Forward File Number				Carry Forward Initial effective date				Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be Paid		Equity			Common Stock, par value $0.001 per share				457	(c)			14,589,546	(1)			$0.6850	(2)		$	9,993,839.01				0.00013810			$	1,380.15				-				-				-				-
Fees Previously Paid		-			-				-				-				-				-				-				-				-				-				-				-
Carry Forward Securities
Carry Forward Securities		-			-				-				-				-				-				-				-				-				-				-				-
		Total Offering Amounts																		$	9,993,839.01							$	1,380.15
		Total Fees Previously Paid																											-
		Total Fee Offsets																										$	1,365.96
		Net Fee Due																										$	14.19

		Registrant or Filer Name		Form or Filing Type		File Number		Initial Filing Date		Filing Date		Fee Offset Claimed				Security Type Associated with Fee Offset Claimed				Security Title Associated with Fee Offset Claimed				Unsold Securities Associated with Fee Offset Claimed				Unsold Aggregate Offering Amount Associated with Fee Offset Claimed				Fee Paid with Fee Offset Source
Rule 457(b) and 0-11(a)(2)
Fee Offset Claims		GT Biopharma, Inc.		Form S-1		333-287963		June 11, 2025		-		$	1,365.96				-				-				-				-				-
Fee Offset Sources		GT Biopharma, Inc.		Form S-1		333-287963		-		June 11, 2025			-				-				-				-				-			$	1,365.96	(3)
Rule 457(p)
Fee Offset Claims
Fee Offset Sources

(1)	Represents shares of Common Stock, par value $0.001 per share (“Common Stock”), of GT Biopharma, Inc. (the “Company”), which consists of (i) 7,219,771 shares of Common Stock issuable upon the conversion of 3,277.78 shares of Series L 10% Convertible Preferred Stock, par value $0.001 per share, (ii) 7,219,775 shares of Common Stock issuable upon the exercise of vested warrants issuable upon exercise of the Greenshoe Rights (as defined in the Registration Statement), and (iii) 150,000 shares of Common Stock issuable upon the exercise of pre-funded warrants, offered for resale by the selling stockholders pursuant to the prospectus contained in this Registration Statement on Form S-1. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the registrant is also registering an indeterminate number of additional shares of common stock issuable by reason of any stock dividend, stock split, recapitalization or other similar transaction.

(2)	Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(c) under the Securities Act. The price per share and aggregate offering price are based on the average of the high and low prices of the registrant’s Common Stock on October 22, 2025, as reported on The Nasdaq Capital Market.

(3)	The Company previously paid $24,159.06 with the respect to 14,439,546 shares of Common Stock included herein based on a maximum aggregate offering price of $157,799,199.58 in connection with its filing of the Registration Statement on Form S-1 (File No. 333-287963) on June 11, 2025 in connection with the Private Placement (as defined in the Registration Statement). In accordance with Rule 457(b) under the Securities Act, the Company is using $1,365.96 of the previously paid fees to offset the filing fee payable in connection with this amendment to this Registration Statement.

N/A